This one took awhile to figure out. The initial behavior suggested other issues.
A little background:
I am building a new 7.8 Site with PVS. The site components were working fine, except for the PVS image’s published application. They would open then immediately close. There wasn’t any indication of an in error in the event log. Upon closer (and quicker) observation, it could be seen that two applications were opening at the same time and closing.